Who I am

Born in France, I trained across Europe, completing a B.Sc. in Health Engineering (France/Germany), an M.Sc. in Radiobiology (United Kingdom) and a PhD in Clinical Medicine at Trinity College Dublin, Ireland, where I now serve as Professor in Radiation Biology and Head of the Discipline of Radiation Therapy.

My career has been driven by a simple scientific question: why do seemingly similar tumours respond differently to radiotherapy? Over the past two decades, this curiosity has shaped a research programme spanning tumour hypoxia, radioresistance, molecular biomarkers, mathematical modelling and, more recently, tumour sex chromosome biology. Together, these studies seek to uncover previously overlooked biological determinants of treatment response and translate them into more precise approaches to cancer care.

I established Applied Radiation Therapy Trinity (ARTT) to embed radiation biology within a multidisciplinary research environment that brings together laboratory science, clinical oncology, medical physics and computational biology. Our current research programme, OSIRIS, builds on this foundation by investigating tumour sex chromosome state as a novel biological determinant of tumour behaviour and radiation response.

Alongside my research, I am passionate about developing the next generation of researchers and strengthening the contribution of radiation biology beyond its traditional boundaries. Through international education, multidisciplinary collaboration and research capacity building, I aim to ensure that biological discovery informs not only scientific understanding, but also clinical practice and ultimately improves outcomes for people living with cancer.