https://www.marignol-lab.org/labfocus daily 1.0 2026-01-12 https://www.marignol-lab.org/about daily 0.75 2026-01-07 https://images.squarespace-cdn.com/content/v1/6034f001d2fad339cc5652ae/1614178388485-U6DYQSL0PFD1IRW4X0FJ/3813-301+new.jpg About Laure Marignol Prof. Laure Marignol, PhD. Radiobiologist, Scientist, Educator. https://www.marignol-lab.org/barriers-to-cancer-cells-destruction daily 0.75 2026-01-07 https://www.marignol-lab.org/predicting-cancer-cell-destruction daily 0.75 2026-01-07 https://www.marignol-lab.org/my-values daily 0.75 2026-01-07 https://images.squarespace-cdn.com/content/v1/6034f001d2fad339cc5652ae/1616581859084-R1I664WAHFS075M8XJW5/Values.png Values The Marignol lab is led by a PI that prides herself in being fair, a value most appreciated by her students and peers. Prof. Marignol has developed her career through the combination of a love of learning, a need to be challenged and an awareness that kindness is key to progress. She believe in embracing the possibility of a second chance and takes pleasure in exploring a hunch, in hearing the perspective of others and in encouraging the scientific community to continue to explore her field. https://www.marignol-lab.org/contact-1 daily 0.75 2021-03-26 https://www.marignol-lab.org/radbio-facts daily 0.75 2021-03-25 https://images.squarespace-cdn.com/content/v1/6034f001d2fad339cc5652ae/1616668569736-F0UZZWSD8YNZISL8HO2C/RadBioFact+dose+response+.png RadBio Facts Did you know? Radiobiology can help clinicians anticipate the impact of a change in radiation dose on tumour and/or normal tissue complication response rate. https://images.squarespace-cdn.com/content/v1/6034f001d2fad339cc5652ae/1616607647712-5YW73X61TKYR79VGOAMS/RadBioFact+tumour+control.png RadBio Facts Did you know? The goal of curative radiotherapy is local tumour control. Most likely to translate into improved patient survival, the probability of success increases with radiation dose. https://images.squarespace-cdn.com/content/v1/6034f001d2fad339cc5652ae/1616668501617-FJGIGI9TSCI5WPV7YPG8/RadBioFact+time.png RadBio Facts Did you know? Radiotherapy should be delivered over a short time and as scheduled. Interruptions can change the radiobiology of tumours and tissues and with it, treatment outcomes. https://images.squarespace-cdn.com/content/v1/6034f001d2fad339cc5652ae/1616668874880-ATB6CXAR9ZIWRNY9KCMY/RB+Fractionation.png RadBio Facts Did you know? Biologically, fractionated radiation doses are less efficient in causing cell death than single doses. Yet fractionated radiotherapy cures disease. https://images.squarespace-cdn.com/content/v1/6034f001d2fad339cc5652ae/1616668816215-Y7B7X9ULQW87S9NE356D/RabBio+and+Phys.png RadBio Facts Did you know? The energy deposition pattern of ionising radiation within cells links physics with biology. This explains why different types of radiation will have different biological effectiveness. A phenomenon that we do exploit in the clinic. https://images.squarespace-cdn.com/content/v1/6034f001d2fad339cc5652ae/1616668929092-IZRO4LT2X9FP7WEPLKP3/DNA+damage+Fact.png RadBio Facts Did you know? Ionising radiation uniquely produces clusters of different types of DNA damage. The damage is random, and this complexity largely contributes to biological toxicity.